The present invention relates to the cloning of a novel cDNA sequence encoding the theta receptor subunit of the GABAA receptor; to stably co-transfected eukaryotic cell lines capable of expressing a GABAA receptor, which receptor comprises the novel theta receptor subunit; and to the use of such cell lines in screening for and designing medicaments which act upon the GABAA receptor.
申请公布号
WO9849293(A1)
申请公布日期
1998.11.05
申请号
WO1998GB01206
申请日期
1998.04.24
申请人
MERCK SHARP & DOHME LIMITED;BONNERT, TIMOTHY, PETER;WHITING, PAUL, JOHN