The murine cDNA (I) for nCL-3 calpain of 2459 bp, its allelic variants encoding a protein having 60-100% homology at the amino acid (aa) level, analogues and derivatives are new. Also new are: (1) the corresponding human cDNA (Ia) of 1975 bp; (2) gene constructs containing (I) and (Ia) plus regulatory sequences; and (3) proteins (II) encoded by (I).
申请公布号
DE19718248(A1)
申请公布日期
1998.11.05
申请号
DE19971018248
申请日期
1997.04.30
申请人
BASF AG, 67063 LUDWIGSHAFEN, DE
发明人
NEIL, T. DEAR, DR., 69123 HEIDELBERG, DE;BOEHM, THOMAS, PROF. DR., 79279 VOERSTETTEN, DE