| 发明名称 |
PERIPHERALLY SELECTIVE KAPPA OPIOID AGONISTS |
| 摘要 |
The novel compounds of formula (I) of the instant invention are peripherally selective kappa opioid agonists useful in the treatment of arthritis, hypertension, pain, inflammation, migraine, inflammatory disorders of the gastrointestinal tract, IBS, and psoriasis. The compounds, novel intermediates useful in their preparation, and pharmaceutical compositions containing them are part of the invention.
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| 申请公布号 |
WO9849158(A1) |
申请公布日期 |
1998.11.05 |
| 申请号 |
WO1998US06485 |
申请日期 |
1998.04.02 |
| 申请人 |
WARNER-LAMBERT COMPANY;HORWELL, DAVID, CHRISTOPHER;OSBORNE, SIMON |
发明人 |
HORWELL, DAVID, CHRISTOPHER;OSBORNE, SIMON |
| 分类号 |
C07D207/10;C07D207/12;C07D295/125;C07D307/81;C07D333/60;C07D405/12;C07D409/12;C07F7/18;(IPC1-7):C07D405/12;A61K31/34;A61K31/38;A61K31/41;C07D295/12 |
主分类号 |
C07D207/10 |
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