发明名称 Compounds
摘要 There are provided novel compounds of formula (I) wherein R<1>, R<2>, R<3>, R<4>, R<5>, A, Q, X, Y, and Z are as defined in the specification, and pharmaceutically acceptable salts thereof, and enantiomers and tautomers thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the enzyme nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease and pain.
申请公布号 SE9803773(D0) 申请公布日期 1998.11.05
申请号 SE19980003773 申请日期 1998.11.05
申请人 ASTRA PHARMACEUTICALS LTD 发明人 ANTHONY *COOK;PETER *HAMLEY;ALAN *TINKER
分类号 A61K31/4427;A61K31/443;A61K31/4433;A61K31/4545;A61K31/4709;A61K31/497;A61P1/00;A61P19/02;A61P29/00;A61P43/00;C07D213/75;C07D401/12;C07D401/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14;(IPC1-7):C07D/ 主分类号 A61K31/4427
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