发明名称 Radiolabeled growth hormone secretagogue
摘要 The present invention is directed to [35S]-N-[1(R)-[(1,2-dihydro-1-methanesulfonylspiro[3H-indole-3,4'-piperidin]-1'-yl)carbonyl]-2-(phenylmethyloxy)ethyl]-2-amino-2-methylpropanamide, and pharmaceutically acceptable salts thereof. This [35S] radioligand is useful in identifying and characterizing cellular receptors which play a role in the activity of growth hormone secretatogogues. In addition, this [35S] radioligand is useful in assays which test compounds for growth hormone secretagogue activity.
申请公布号 US5830433(A) 申请公布日期 1998.11.03
申请号 US19960768368 申请日期 1996.12.17
申请人 MERCK & CO., INC. 发明人 DEAN, DENNIS C.;MELILLO, DAVID G.;NARGUND, RAVI;VAN DER PLOEG, LEONARDUS;PONG, SHENG-SHUNG;SCHAEFFER, JAMES M.;SMITH, ROY G.
分类号 A61K51/04;C07K5/06;(IPC1-7):A61K51/00;C07D471/10 主分类号 A61K51/04
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