发明名称 |
Radiolabeled growth hormone secretagogue |
摘要 |
The present invention is directed to [35S]-N-[1(R)-[(1,2-dihydro-1-methanesulfonylspiro[3H-indole-3,4'-piperidin]-1'-yl)carbonyl]-2-(phenylmethyloxy)ethyl]-2-amino-2-methylpropanamide, and pharmaceutically acceptable salts thereof. This [35S] radioligand is useful in identifying and characterizing cellular receptors which play a role in the activity of growth hormone secretatogogues. In addition, this [35S] radioligand is useful in assays which test compounds for growth hormone secretagogue activity.
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申请公布号 |
US5830433(A) |
申请公布日期 |
1998.11.03 |
申请号 |
US19960768368 |
申请日期 |
1996.12.17 |
申请人 |
MERCK & CO., INC. |
发明人 |
DEAN, DENNIS C.;MELILLO, DAVID G.;NARGUND, RAVI;VAN DER PLOEG, LEONARDUS;PONG, SHENG-SHUNG;SCHAEFFER, JAMES M.;SMITH, ROY G. |
分类号 |
A61K51/04;C07K5/06;(IPC1-7):A61K51/00;C07D471/10 |
主分类号 |
A61K51/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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