发明名称 |
Hybridization and amplification of nucleic acids encoding mpl ligand |
摘要 |
Isolated mpl ligand, isolated DNA encoding mpl ligand, and recombinant methods of preparing mpl ligand are disclosed. These mpl ligands are shown to influence the replication, differentiation or maturation of blood cells, especially megakaryocyte progenitor cells. Accordingly, these compounds are used for treatment of thrombocytopenia.
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申请公布号 |
US5830647(A) |
申请公布日期 |
1998.11.03 |
申请号 |
US19950429764 |
申请日期 |
1995.04.26 |
申请人 |
GENENTECH, INC. |
发明人 |
EATON, DAN L.;DE SAUVAGE, FREDERIC J. |
分类号 |
A61K38/00;A61K38/19;C07K14/52;C12N;C12N1/21;C12N5/10;C12N15/12;C12N15/19;C12N15/63;(IPC1-7):C12Q1/68;C12P19/34;C07H21/04;C07K14/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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