摘要 |
PCT No. PCT/GB93/00034 Sec. 371 Date Aug. 11, 1994 Sec. 102(e) Date Aug. 11, 1994 PCT Filed Jan. 8, 1993 PCT Pub. No. WO93/13803 PCT Pub. Date Jul. 22, 1993A method for producing a drug system which is a reversible gelled matrix with entrapped drug. The gel is made by combining a polysaccharide, such as dextran, a polymer of glucose, with a natural macromolecule, such as the lectin, concanavalin A, with binding sites for monomers of the polysaccharide. The drug is released in response to exposure of the matrix to free carbohydrate containing the monomer of the polysaccharide for which the natural macromolecule binds.
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