| 发明名称 |
VECTORS AND COMPOUNDS FOR EXPRESSION OF ZYMOGEN FORMS OF HUMAN PROTEIN C |
| 摘要 |
A method for the recombinant production of zymogen forms of human protein C is described. These zymogen forms differ from native zymogen protein C in their increased sensitivity to activation by thrombin and thrombin/thrombomodulin. DNA compounds, vectors, and transformants useful in the method are also disclosed.
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| 申请公布号 |
CA1340111(C) |
申请公布日期 |
1998.11.03 |
| 申请号 |
CA19880587009 |
申请日期 |
1988.12.23 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
BANG, NILS ULRIK;EHRLICH, HARTMUT JOSEF;GRINNELL, BRIAN WILLIAM;YAN, SAU-CHI BETTY |
| 分类号 |
C12N9/50;A61K31/70;A61K38/43;A61K38/46;A61P7/04;C07H21/04;C07K14/00;C07K14/745;C07K19/00;C12N5/10;C12N9/64;C12N15/09;C12N15/12;C12N15/15;C12R1/91;(IPC1-7):C12N15/57;A61K38/48 |
主分类号 |
C12N9/50 |
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