发明名称 |
Crystalline hydrochloride of (R)-(-)-2-(N-[4-(1,1-dioxido-3-oxo-2,3-dihydro-benzisothiazol-2-yl-)-butyl]-aminomethyl)-chroman |
摘要 |
The invention relates to the crystalline form of the hydrochloride of the compound (R)-(-)-2-{N-[4-(1,1-dioxido-3-oxo-2,3-dihydro-benzisothiazol-2-yl)-butyl]-aminomethyl}-chroman, which is present as a stable form at room temperature. The crystalline modification V of the hydrochloride is suitable in particular for the preparation of solid medicaments, in particular of medicaments for the treatment of neuronal degenerations.
|
申请公布号 |
US5830908(A) |
申请公布日期 |
1998.11.03 |
申请号 |
US19960752348 |
申请日期 |
1996.11.19 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
GRUNENBERG, ALFONS;BREHM, OLIVER;CONRAD, MICHAEL;SEIDEL, DIETRICH |
分类号 |
A61K31/352;A61K31/425;A61K31/54;A61P25/00;A61P25/28;C07D275/06;C07D311/58;C07D417/12;(IPC1-7):A61K31/425 |
主分类号 |
A61K31/352 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|