| 发明名称 |
A method of treating cancer |
| 摘要 |
The present invention relates to methods of treating cancer using a combination of a compound which is an integrin antagonist and a compound which is an inhibitor of farnesyl-protein transferase, which methods comprise administering to said mammal, either sequentially in any order or simultaneously, amounts of at least two therapeutic agents selected from a group consisting of a compound which is an integrin antagonist and a compound which is an inhibitor of farnesyl-protein transferase. The invention also relates to methods of preparing such compositions. |
| 申请公布号 |
AU6953298(A) |
申请公布日期 |
1998.10.30 |
| 申请号 |
AU19980069532 |
申请日期 |
1998.04.06 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
MARK E. DUGGAN;GEORGE D. HARTMAN;DAVID C. HEIMBROOK;ALLEN I. OLIFF |
| 分类号 |
A61K31/197;A61K31/195;A61K31/198;A61K31/216;A61K31/223;A61K31/365;A61K31/366;A61K31/404;A61K31/4164;A61K31/4184;A61K31/425;A61K31/426;A61K31/437;A61K31/4375;A61K31/44;A61K31/4439;A61K31/444;A61K31/4545;A61K31/472;A61K31/495;A61K31/496;A61K31/497;A61K31/505;A61K31/506;A61K45/00;A61K45/06;A61P35/00;C07D209/12;C07D213/74;C07D217/22;C07D233/64;C07D233/88;C07D235/30;C07D239/14;C07D239/22;C07D239/42;C07D241/04;C07D277/20;C07D277/40;C07D309/30;C07D401/06;C07D401/10;C07D401/12;C07D401/14;C07D403/06;C07D403/10;C07D403/14;C07D471/04 |
主分类号 |
A61K31/197 |
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