发明名称 METHOD FOR INHIBITING INTRACELLULAR VIRAL REPLICATION
摘要 There is disclosed a method of preventing or delaying the occurrence of acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus (HIV) seropositive humans by administering an effective amount of a compound that inhibits cellular signaling through a specific phospholipid-based cellular signaling and signal amplification pathway. The invention further provides a method for preventing or delaying clinical symptoms of a group of viral diseases wherein the viral disease is mediated by host cell viral replication. The invention provides an advantage by attacking host cellular signaling mechanisms to prevent the development of drug resistance from rapidly mutating viruses.
申请公布号 WO9834601(A3) 申请公布日期 1998.10.29
申请号 WO1998US02622 申请日期 1998.02.10
申请人 CELL THERAPEUTICS, INC. 发明人 LEUNG, DAVID, W.;UNDERINER, GAIL, E.;SINGER, JACK, W.
分类号 A61K31/4035;A61K31/445;A61K31/472;A61K31/513;A61K31/522;C12N15/48 主分类号 A61K31/4035
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