发明名称 |
NOVEL DNAS AND PROCESS FOR PRODUCING PROTEINS BY USING THE SAME |
摘要 |
<p>DNAs having the nucleotide sequences of the Sequences No. 1 and No. 2 in the Sequence Table and a process for producing a protein which comprises inserting these DNAs into expression vectors to thereby produce a protein having molecular weights of about 60 kD (under reductive conditions) and about 60 kD and 120 kD (under non-reductive conditions) and being capable of inhibiting formation of osteoclast. These proteins are useful in the treatment of osteoporosis and rheumatism.</p> |
申请公布号 |
EP0874045(A1) |
申请公布日期 |
1998.10.28 |
申请号 |
EP19970935810 |
申请日期 |
1997.08.19 |
申请人 |
SNOW BRAND MILK PRODUCTS CO., LTD. |
发明人 |
NAKAGAWA, NOBUAKI;YASUDA, HISATAKA;MORINAGA, TOMONORI |
分类号 |
C12N15/09;A61K38/00;A61P43/00;C07H21/04;C07K14/51;C07K14/52;C12N1/21;C12N5/10;C12P21/02;C12R1/19;C12R1/91;(IPC1-7):C12N15/00;C12P21/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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