| 发明名称 |
Integrin ligand ITGL-TSP |
| 摘要 |
<p>ITGL-TSP polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ITGL-TSP polypeptides and polynucleotides in the design of protocols for the treatment of, angiogenic diseases (cancer, cancer metastasis, chronic inflammatory disorders, rheumatoid arthritis, atherosclerosis, macular degeneration, diabetic retinopathy), restenosis, Alzheimer's disease and tissue remodeling, among others, and diagnostic assays for such conditions.</p> |
| 申请公布号 |
EP0874050(A2) |
申请公布日期 |
1998.10.28 |
| 申请号 |
EP19980300575 |
申请日期 |
1998.01.27 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION;SMITHKLINE BEECHAM PLC;HUMAN GENOME SCIENCES, INC. |
发明人 |
JONAK, ZDENKA L.;TRULLI, STEPHEN H.;FRONWALD, JAMES A.;HASTINGS, GREGG A.;TERRETT, JONATHAN A. |
| 分类号 |
C12N15/09;C12N15/15;A61K31/70;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P9/00;A61P9/10;A61P25/28;A61P27/02;A61P29/00;A61P35/00;C07K14/47;C07K14/745;C07K14/78;C07K16/18;C12N1/21;C12N5/10;C12N9/64;C12P21/02;C12Q1/02;C12Q1/68;C12R1/19;G01N33/68;(IPC1-7):C12N15/15 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
