TRICYCLIC COMPOUNDS

摘要

Tricyclic compounds of general formula (I) and pharmacologically acceptable salts thereof, which are useful for the treatment of pollakiuria and enuresis, wherein R1 is hydrogen, substituted or unsubstituted lower alkyl or the like; X1-X2-X3 is CR5= CR6-CR7=CR8 (wherein R5, R6, R7 and R8 are each independently hydrogen, substituted or unsubstituted lower alkyl, hydroxyl, substituted or unsubstituted lower alkoxy or the like), N(O)m=CR5-CR6-CR7 (wherein R5, R6 and R7 are each the same as defined above; and m is 0 to 1), S-CR7=CR8 (wherein R7 and R8 are each the same as defined above) or the like; R2 is hydrogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkoxy, a substituted or unsubstituted N-substituted heterocyclic group or a group of general formula (a); (wherein n is 0 or 1; R3 and R4 are each independently hydrogen, substituted or unsubstituted lower alkyl, trifluoromethyl or the like, or alternatively R3 and R4 may be united to form cyclic alkyl; and Q is hydroxyl, halogeno or the like); and Y is -CH2SO2-, SCH2-, -SOCH2-, -SO2CH2- or the like.