HAIR FOLLICLE DNA DELIVERY SYSTEM

摘要

A novel method and delivery system for delivering nucleic acids to a mammalian cell in vivo by topical application of the nucleic acid and the delivery system has been developed. The method and delivery system utilize a liposomal composition having non-ionic lipids and a cationic lipid. The method and delivery system are particularly well suited for gene therapy of dermatological disorders including neoplastic disease and alopecia by topical administration.