发明名称 5,6,7-TRISUBSTITUTED-4-AMINOPYRIDOL[2,3-D]PYRIMIDINE COMPOUNDS
摘要 A compound having formula (II) wherein R1, R2, R3, R4 and R5 are defined, a method for inhibiting adenosine kinase by administering a compound thereof, a pharmaceutical composition comprising a therapeutically effective amount of a compound thereof above in combination with a pharmaceutically acceptable carrier, a method of treating cerebral ischemia, epilepsy, pain, nociperception, inflammation and sepsis in a mammal in need of such treatment, comprising administering to the mammal a therapeutically effective amount of a compound thereof, and methods for preparation thereof.
申请公布号 CA2286592(A1) 申请公布日期 1998.10.22
申请号 CA19982286592 申请日期 1998.04.13
申请人 ABBOTT LABORATORIES 发明人 GU, YU GUI;PERNER, RICHARD J.;BHAGWAT, SHRIPAD S.
分类号 A61P25/04;A61K31/519;A61P1/00;A61P3/10;A61P9/00;A61P25/08;A61P25/18;A61P25/22;A61P29/00;A61P31/00;A61P37/06;A61P43/00;C07D471/04;(IPC1-7):C07D471/04;A61K31/505 主分类号 A61P25/04
代理机构 代理人
主权项
地址