NOVEL PROTEIN BINDING TO OSTEOCLASTOGENESIS INHIBITORY FACTOR AND PROCESS FOR PRODUCING THE SAME

摘要

A novel protein binding to osteoclastogenesis inhibitory factor (OCIF) (OCIFbinding molecule; OBM). A DNA encoding the above protein; a protein having the amino acid sequence encoded by this DNA; a process for producing this protein by the genetic engineering technique; and medicinal compositions containing this protein. A method for screening a substance regulating the expression of the above protein, a substance inhibiting or modifying the biological activity of the above protein, or a receptor binding to the above protein and thus mediating its function with the use of the above protein and the DNA thereof; substances thus obtained; and medicinal compositions containing the substances thus obtained. An antibody against the above protein; a method for assaying the above protein by using the antibody; and drugs containing the antibody.