MODULAR ASSEMBLY FOR REAGENTLESS AFFINITY SEPARATION AND DETECTION OF ANALYTE
摘要
The invention provides a reagentless assay kit for analyte in a sample comprising a modular affinity assembly including at least one sensor unit comprising a ligand having binding affinity for the analyte (affinity module) operatively associated with a reporter probe (reporter module) responsive to changes in the sensor unit induced by analyte/receptor complex formation by transduction of a characteristic detectable signal. Assays employing the modular assembly are also provided.
申请公布号
CA2285957(A1)
申请公布日期
1998.10.22
申请号
CA19982285957
申请日期
1998.04.10
申请人
THE UNIVERSITY OF NEW MEXICO
发明人
HAMPTON, PHILIP;JAIN, RAVINDER K.;SKLAR, LARRY A.;TENDER, LEONARD;OPPERMAN, KIMBERLY;RABINOVICH, EMMANUIL;LOPEZ, GABRIEL P.