RECOMBINANT PROTEINS OF A PAKISTANI STRAIN OF HEPATITIS E AND THEIR USE IN DIAGNOSTIC METHODS AND VACCINES
摘要
The invention relates to the expression of open reading frame 2 (ORF-2) proteins of a strain of hepatitis E virus from Pakistan (SAR-55) in a eukaryotic expression system. The expressed proteins can serve as an antigen in diagnostic immunoassays and/or as an immunogen or vaccine to protect against infection by hepatitis E.
申请公布号
CA2286399(A1)
申请公布日期
1998.10.22
申请号
CA19982286399
申请日期
1998.04.09
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SEC RETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;NOVAVAX, INC.
发明人
EMERSON, SUZANNE U.;PURCELL, ROBERT H.;TSAREV, SERGEI A.;ROBINSON, ROBIN A.
