SORPTION AGENT CONTAINING NUCLEOTIDE, FOR AFFINITY CHROMATOGRAPHY

摘要

The invention relates to sorption agents for affinity chromatography on the basis of base carriers containing hydroxyl groups, polymers being covalent-bonded on the surfaces of said base carriers. According to the invention, the base carrier contains aliphatic hydroxyl groups, the covalent-bonded polymers are bonded to the base carrier via a terminal monomer unit, the monomer units are bonded linearly, and the polymers contain monomer units of formula (I) wherein R<1>, R<2> and R<3> independently mean H or CH3, R<4> means H, C1-C5 alkyl or C6-C12 aryl, n is a whole number between 1 and 5, and one of the radicals X is OH and the other radical Y is a radical containing nucleoside bonded via an alkylene radical. The invention also relates to the production and the use of the inventive sorption agents.