发明名称 COMPOUNDS
摘要 There are provided novel compounds of formula (I), wherein A represents a benzo ring; a six membered heterocyclic aromatic ring containing 1 to 3 nitrogen atoms; or a five membered heterocyclic aromatic ring containing 1 to 3 heteroatoms which may be the same or different and are selected from O, N and S; and R1, R2, R3 and X are as defined in the Specification and pharmaceutically acceptable salts thereof and enantiomers and tautomers thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment and prophylaxis of inflammatory disease and pain.
申请公布号 CA2286789(A1) 申请公布日期 1998.10.22
申请号 CA19982286789 申请日期 1998.04.07
申请人 ASTRA PHARMACEUTICALS LTD. 发明人 HAMLEY, PETER;TINKER, ALAN;MCINALLY, THOMAS
分类号 A61P25/04;A61K31/438;A61K31/4747;A61K31/537;A61K31/547;A61P11/06;A61P29/00;A61P43/00;C07D471/10;C07D471/20;C07D495/20;C07D498/10;C07D513/10;(IPC1-7):C07D498/10;A61K31/445;A61K31/535 主分类号 A61P25/04
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