发明名称 CHELATING AGENTS
摘要 The invention provides a complexant compound of formula (I): R3S(CR12)nN(R2)i(CR12)nX(CR12)nN(R2)i(CR12)nSR3, (wherein each n, which may be the same or different, is an integer 2, 3 or 4 (preferably 2); each i, which may be the same or different, represents 0 or 1; each R3, which may be the same or different, is H or a thiol protecting group, preferably a protecting group; X is O, S, N, NR4 or a substituted phosphorus (e.g. oxo substituted phosphorus), preferably S or N; each R4, which may be the same or different, is hydrogen or an optionally substituted organic group; each R2, which may be the same or different, is hydrogen or an optionally substituted organic group; each R1, which may be the same or different, is hydrogen or an optionally substituted organic group, or a moiety CR12 may represent a carbonyl group or two, three or four R1S on two different carbons together with those carbons and any intervening atoms may represent an optionally substituted saturated or unsaturated homocyclic or heterocyclic ring; and preferably, at least one CR12 moiety is other than CH2 or CH(CH3)) or a salt or complex thereof, wherein optionally at least one of the R1, R2, R3 and R4 moieties is coupled directly or indirectly to a vector moiety.
申请公布号 CA2286790(A1) 申请公布日期 1998.10.22
申请号 CA19982286790 申请日期 1998.04.14
申请人 NYCOMED IMAGING AS 发明人 SINGH, JASBIR;YU, SHI-BAO
分类号 C07D233/14;A61K49/00;A61K49/04;A61K49/08;A61K51/00;A61K51/04;A61P35/00;C07C323/59;C07C323/60;C07D213/52;C07D213/53;C09K3/00;(IPC1-7):A61K51/04 主分类号 C07D233/14
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