发明名称 |
5,6,7-TRISUBSTITUTED-4-AMINOPYRIDOL[2,3-D]PYRIMIDINE COMPOUNDS |
摘要 |
A compound having formula (II) wherein R<1>, R<2>, R<3>, R<4> and R<5> are defined, a method for inhibiting adenosine kinase by administering a compound thereof, a pharmaceutical composition comprising a therapeutically effective amount of a compound thereof above in combination with a pharmaceutically acceptable carrier, a method of treating cerebral ischemia, epilepsy, pain, nociperception, inflammation and sepsis in a mammal in need of such treatment, comprising administering to the mammal a therapeutically effective amount of a compound thereof, and methods for preparation thereof.
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申请公布号 |
WO9846604(A1) |
申请公布日期 |
1998.10.22 |
申请号 |
WO1998US07201 |
申请日期 |
1998.04.13 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
BHAGWAT, SHRIPAD, S.;PERNER, RICHARD, J.;GU, YU, GUI |
分类号 |
A61P25/04;A61K31/519;A61P1/00;A61P3/10;A61P9/00;A61P25/08;A61P25/18;A61P25/22;A61P29/00;A61P31/00;A61P37/06;A61P43/00;C07D471/04;(IPC1-7):C07D471/04;A61K31/505 |
主分类号 |
A61P25/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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