发明名称 |
THERAPEUTIC, PROPHYLACTIC AND DIAGNOSTIC AGENT FOR CANCER, USEFUL FOR CHARACTERISING CANCER CELLS WITH INDIVIDUAL PROPERTIES |
摘要 |
A therapeutic or prophylactic agent for cancer is disclosed which damages the membrane and kills cancer cells, in particular of the blood-forming system, having membrane protein aggregates which contain several core histones or largely core-like histones and/or their parts. The therapeutic or prophylactic agent contains at least one pure histone or its active sequence section selected from the group composed of histone H1, H1 subtypes, H2A, H2B, H2A:H2B dimer, H3 and H4, covalent modified histones of the above-mentioned type and/or their active sections and functionally and structurally similar proteins (protamines, histone-like proteins of prokaryotic and archae bacteria).
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申请公布号 |
CA2292757(A1) |
申请公布日期 |
1998.10.22 |
申请号 |
CA19982292757 |
申请日期 |
1998.04.09 |
申请人 |
SYMBIOTEC GESELLSCHAFT ZUR FORSCHUNG UND ENTWICKLUNG AUF DEM GEBIET DER BIOTECHNOLOGIE MBH |
发明人 |
ZEPPEZAUER, MICHAEL;LEINENBACH, HANS-PETER;FASSBENDER, CORDULA;CLASS, REINER |
分类号 |
A61K38/00;A61K38/16;A61K38/17;A61P7/00;A61P35/00;C07K14/705;(IPC1-7):A61K38/16;G01N33/574 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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