发明名称 Method of attenuating arterial stenosis
摘要 A method is disclosed for attenuating stenosis after balloon angioplasty. The method comprises administering to a host parenterally or locally to the luminal surface of the blood vessel subjected to said balloon angioplasty an effective amount of tissue factor pathway inhibitor (TFPI) for a prolonged period of time sufficient to substantially reduce the extent of restenosis. An exemplary amount of the TFPI is from about 0.5 mg/kg to about 6 mg/kg during a prolonged administration of about twelve (12) hours to 36 hours.
申请公布号 US5824644(A) 申请公布日期 1998.10.20
申请号 US19960675122 申请日期 1996.07.03
申请人 G. D. SEARLE & CO. 发明人 ABENDSCHEIN, DANA R.
分类号 A61K38/57;(IPC1-7):A61K38/00;C07K14/00;A61F13/00 主分类号 A61K38/57
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