发明名称 |
Recombinant gas vesicles and uses thereof |
摘要 |
The invention features a composition that includes a substantially pure recombinant gas vesicles which have at least one heterologous peptide inserted into at one of their structural proteins. The recombinant gas vesicle, when administered to a mammal, is capable of eliciting antibodies which specifically bind to the heterologous peptide. The heterologous peptide can be any peptide against which one wishes to raise antibodies, e.g., a peptide found in the gp12O protein of human immunodeficiency virus (HIV).
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申请公布号 |
US5824309(A) |
申请公布日期 |
1998.10.20 |
申请号 |
US19960759444 |
申请日期 |
1996.12.05 |
申请人 |
UNIVERSITY OF MASSACHUSETTS |
发明人 |
DASSARMA, SHILADITYA;MORSHED, FAZEELA;STUART, ELIZABETH;BLACK, SAMUEL |
分类号 |
A61K38/00;A61K39/385;C07K14/16;C07K14/195;C07K14/215;(IPC1-7):A61K39/21;A61K39/02;A61K39/295 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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