Coiled sheet graft stent and methods of making and use

摘要

A prosthesis is provided for treatment of aneurysms, occlusive disease of vessels and body organs, and arterio-venous fistulas, comprising an expandable coiled sheet portion having a biocompatible graft affixed thereto. The graft material, preferably a polytetrafluoroethylene ("PTFE") or polyesther material, is affixed to the coiled sheet portion by sintering, suturing, or bonding using a biocompatible adhesive. The coiled sheet portion comprises a lattice formed from a biocompatible material, and may include one or more rows of locking teeth adjacent one edge of the coiled sheet that interengage openings in an opposing edge of the coiled sheet portion to retain the prosthesis at a desired expanded diameter. The prosthesis has a small delivery profile, making it suitable for use in a variety of body vessels. Methods of making and deploying the prosthesis are also provided.