Heterocyclic acyldipeptides, processes for the preparation thereof and pharmaceutical compositions containing the same

摘要

PCT No. PCT/SI94/00003 Sec. 371 Date Jan. 4, 1996 Sec. 102(e) Date Jan. 4, 1996 PCT Filed Apr. 21, 1994 PCT Pub. No. WO94/24152 PCT Pub. Date Oct. 27, 1994Heterocyclic acyldipeptides of the formula I ulphur atom or a -CH2-group; R1, R2 and R3 individually represent hydrogen or certain organic groups; R4 and R5, which are identical or different, represent an OR6 or NHR6 group, wherein R6 is hydrogen or certain organic groups; Y represents a -CH2-, =CH- or =N- group; A represents a -(CH2)3- group when Y is -CH2-, the two rings being transcondensed, or a <IMAGE> wherein R7 represents H, F, Br, Cl, nitro, or certain organic groups when Y is =CH- or =N-; and their pharmaceutically acceptable salts are provided. These heterocyclic acyldipeptides and their salts are useful as active compounds in medicaments having immunostimulatory and antitumor activity.