发明名称 Process for preparing dibenzo-1-carboxamido-1,4-azabicyclo(3.2.1.) octanes
摘要 Disclosed are a process and novel compounds useful for preparing compounds of formula (A) wherein R1 and R2 independently represent hydrogen, inorganic or optionally substituted organic substituents; R3 is hydrogen, or an optionally substituted organic group; and R4 and R5 are as defined herein, the process comprising (a) converting a dibenzocycloheptene into a 5-hydroxyaminodibenzocycloheptene; (b) converting the 5-hydroxyaminodibenzocycloheptene into a 12-hydroxy-10,11-dihydrodibenzocycloheptene; and (c) removing the 12-hydroxy group to yield a 10,11-dihydro-dibenzocycloheptene.
申请公布号 AU6765598(A) 申请公布日期 1998.10.12
申请号 AU19980067655 申请日期 1998.03.20
申请人 NEUROGEN CORPORATION 发明人 PHILIP D MAGNUS
分类号 C07C239/12;C07D451/02 主分类号 C07C239/12
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