摘要 |
This invention pertains to methods and compositions for increasing the aqueous solubility and bio-availability of bioactive agents by using an amino alcohol moiety as a bridge between a carboxy containing agent and a phospholipid, where the amino alcohol is selected from the group consisting of spingosine, 2-aminoglycerol, aminoethanol, serine, threonine, tyrosine, tyramine or similar compounds and the phospholipid is phosphocholine or related compounds.
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