发明名称 PHOSPHOLIPID DRUG DERIVATIVES
摘要 This invention pertains to methods and compositions for increasing the aqueous solubility and bio-availability of bioactive agents by using an amino alcohol moiety as a bridge between a carboxy containing agent and a phospholipid, where the amino alcohol is selected from the group consisting of spingosine, 2-aminoglycerol, aminoethanol, serine, threonine, tyrosine, tyramine or similar compounds and the phospholipid is phosphocholine or related compounds.
申请公布号 WO9843676(A1) 申请公布日期 1998.10.08
申请号 WO1998US05833 申请日期 1998.03.25
申请人 AMUR PHARMACEUTICALS, INC.;CHASALOW, FRED, I. 发明人 CHASALOW, FRED, I.
分类号 A61K47/44;(IPC1-7):A61K47/44 主分类号 A61K47/44
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