| 摘要 |
A method of lowering plasma levels of Lp(a) or inhibiting the generation of apo(a) in a human by administering an effective amount of a compound of formula (I): <IMAGE> (I) wherein: R1 is hydrogen or alkyl; A, B, D, E, G, R2 and R3 each are hydrogen, and R4 is hydrogen in the beta -position; or R2 with R4, R4 with A, A with R3, B with D, D with E, or G with R2 is a bond, and the other substituents are each hydrogen; or R2 is alkyl in the beta -position and A, B, D, E, G, R3 and R4 are each hydrogen; or R3 is alkoxy in the beta -position and A, B, D, E, G, R2 and R4 are each hydrogen; or R4 is hydrogen in the alpha -position and A, B, D, E, G, R2 and R3 are each hydrogen; and R5 is methyl or ethyl, is disclosed. |
