摘要 |
<p>Inhibitors for the formation of glycosylated protein denaturation products containing as the active ingredient 1,4-benzothiazine-2-acetic acid compounds represented by general formula (I) or pharmceutically acceptable salts thereof (wherein R?1 and R2¿ represent each H, halogeno, lower alkyl, lower alkoxy, lower alkylthio, trifluoromethyl or trifluoromethoxy; R3 represents optionally esterified carboxy; R?4, R5, R6 and R7¿ represent each H, halogeno, lower alkyl, lower alkoxy or trifluoromethyl; and X represents O or S) and preventives/remedies for diseases caused or worsened by the formation of glycosylated protein denaturation products.</p> |