| 摘要 |
PCT No. PCT/US94/10479 Sec. 371 Date Mar. 14, 1996 Sec. 102(e) Date Mar. 14, 1996 PCT Filed Sep. 16, 1994 PCT Pub. No. WO95/07926 PCT Pub. Date Mar. 23, 1995The present invention relates to compounds of formula (I), wherein carbons 1 and 2 are joined by either a single or a double bond; R1 is hydrogen or methyl; R2 is hydrogen or methyl; R3 is (A) or (B) wherein X, W, Z, R4, R5, R6, R7 and R8 are various groups, and pharmaceutically acceptable solvates thereof and their use in the treatment of androgen responsive and mediated diseases. <IMAGE> (1) <IMAGE> (A) <IMAGE> (B)
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