发明名称 Immunogenic peptides, antibodies and uses thereof relating to CD4 receptor binding
摘要 Immunogenic peptides containing amino acid residues which define a binding site to a CD4 receptor are disclosed. Antibodies to these peptides are also disclosed. Methods of reducing the ability of a gp120 env protein to bind to CD4 are also disclosed. Methods of treatment and prophylaxis using these antibodies and peptides are also described.
申请公布号 US5817316(A) 申请公布日期 1998.10.06
申请号 US19920858165 申请日期 1992.03.26
申请人 DANA-FARBER CANCER INSTISTUTE 发明人 SODROSKI, JOSEPH G.;HASELTINE, WILLIAM A.;FURMAN, CRAIG D.;OLSHEVSKY, UDY;HELSETH, EIRIK;WYATT, RICHARD;THALI, MARKUS
分类号 A61K39/21;A61K38/00;A61K39/00;A61K39/395;A61P31/12;A61P31/18;C07K14/00;C07K14/155;C07K14/16;C07K14/705;C07K16/00;C07K16/10;C07K19/00;C12N15/02;C12P21/02;C12P21/08;C12R1/91;(IPC1-7):A61K39/21;A61K39/12;C07K1/00 主分类号 A61K39/21
代理机构 代理人
主权项
地址