发明名称 |
Immunogenic peptides, antibodies and uses thereof relating to CD4 receptor binding |
摘要 |
Immunogenic peptides containing amino acid residues which define a binding site to a CD4 receptor are disclosed. Antibodies to these peptides are also disclosed. Methods of reducing the ability of a gp120 env protein to bind to CD4 are also disclosed. Methods of treatment and prophylaxis using these antibodies and peptides are also described.
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申请公布号 |
US5817316(A) |
申请公布日期 |
1998.10.06 |
申请号 |
US19920858165 |
申请日期 |
1992.03.26 |
申请人 |
DANA-FARBER CANCER INSTISTUTE |
发明人 |
SODROSKI, JOSEPH G.;HASELTINE, WILLIAM A.;FURMAN, CRAIG D.;OLSHEVSKY, UDY;HELSETH, EIRIK;WYATT, RICHARD;THALI, MARKUS |
分类号 |
A61K39/21;A61K38/00;A61K39/00;A61K39/395;A61P31/12;A61P31/18;C07K14/00;C07K14/155;C07K14/16;C07K14/705;C07K16/00;C07K16/10;C07K19/00;C12N15/02;C12P21/02;C12P21/08;C12R1/91;(IPC1-7):A61K39/21;A61K39/12;C07K1/00 |
主分类号 |
A61K39/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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