发明名称 |
Method and apparatus for controlling concentrations in vivos and in tubing systems |
摘要 |
A method and apparatus for maximizing the total amount of blood processed during an apheresis procedure by optimizing the concentration of anticoagulant in a donor/patient and the associated extracorporeal tubing set is provided. A simplified model of anticoagulant accumulation in a donor/patient's body is used to calculate an optimal anticoagulant infusion rate profile to the donor/patient during a blood processing procedure. A maximum acceptable anticoagulant concentration in the donor/patient acts as an upper limit on the rate at which anticoagulant may be infused to the donor/patient using the optimized infusion rate profile. A minimum acceptable anticoagulant level acts as a lower limit in optimally controlling the anticoagulant concentration in the extracorporeal tubing set. Both the maximum acceptable anticoagulant level in the donor/patient and the minimum acceptable anticoagulant level in the extracorporeal tubing set may be customized for a specific donor/patient thereby allowing the optimized infusion rate profile and the extracorporeal tubing set anticoagulant concentration to be customized for the specific patient. |
申请公布号 |
US5817042(A) |
申请公布日期 |
1998.10.06 |
申请号 |
US19960622642 |
申请日期 |
1996.03.27 |
申请人 |
COBE LABORATORIES, INC. |
发明人 |
LANGLEY, ROBERT W.;WAEG, GEERT VAN;DUMONT, LARRY JOE |
分类号 |
A61M1/30;A61M1/34;A61M1/36;(IPC1-7):A61M37/00 |
主分类号 |
A61M1/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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