发明名称 |
Genes for the synthesis of pyrrolnitrin |
摘要 |
The present invention is directed to the production of an antipathogenic substance (APS) in a host via recombinant expression of the polypeptides needed to biologically synthesize the APS. Genes encoding polypeptides necessary to produce particular antipathogenic substances are provided, along with methods for identifying and isolating genes needed to recombinantly biosynthesize any desired APS. The cloned genes may be transformed and expressed in a desired host organisms to produce the APS according to the invention for a variety of purposes, including protecting the host from a pathogen, developing the host as a biocontrol agent, and producing large, uniform amounts of the APS.
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申请公布号 |
US5817502(A) |
申请公布日期 |
1998.10.06 |
申请号 |
US19960729214 |
申请日期 |
1996.10.09 |
申请人 |
NOVARTIS FINANCE CORPORATION |
发明人 |
LIGON, JAMES M.;HILL, DWIGHT STEVEN;LAM, STEPHEN TING;HAMMER, PHILIP E.;VAN PE, KARL-HEINZ;KIRNER, SABINE |
分类号 |
A01H5/00;A01N37/44;A01N63/00;C07K14/195;C07K14/21;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/31;C12N15/52;C12N15/78;C12N15/82;C12P17/08;C12P17/10;C12P21/02;C12R1/91;(IPC1-7):C12N1/20 |
主分类号 |
A01H5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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