摘要 |
<p>The new 3-cycloalkyl propanamides show antiphlogistic effect.They have the general formulawhere R1 means cycloalkyl radical with 3 to 6 carbon atoms, R2 ishydrogen atom or alkyl radical containing from 1 to 3 carbonatoms, R3-R7 are the same or different and mean hydrogen atom,halogen atom, alkyl linear or branching radical with 1 to 6 carbonatoms, alkoxy linear or branching radical with 1 to 6 carbonatoms, thioalkyl radical with 1 to 6 carbon atoms, one of theradicals - (CH2)m - CF3, - O -(CH2)m - CF3, - S - (CH2)m - CF3,where m is an integer from 0 to 3, one of the radicals - CF2 -Ha1, - OCF2 - Ha1,or O(CF2)n - CF - Hal3 - CF3, where n is an integer from 1 to 3,Hal1 and Hal2 are the same or different, Ha1 and Hal3 are halogenatoms, or R3-R7 are the same or different and form a nitrogroup,azidogroup, nitrilegroup, - CO - R' group, where R' is hydroxy,alkoxy or alkyl radical including from 1 to 3 carbon atoms and R4and R5 form together the group - O - CH2 - O -.10 claims</p> |