发明名称 AMIDINE AND ISOTHIOUREA DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE.
摘要 There are provided novel compounds of formula (I), wherein X, R1, R2, R3, R4 and R5 are as defined in the specification and optical isomers and racemates thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy.
申请公布号 MX9803453(A) 申请公布日期 1998.09.30
申请号 MX19980003453 申请日期 1998.04.30
申请人 ASTRA AKTIEBOLAG 发明人 JAMES MACDONALD;JAMES MATZ;WILLIAM SHAKESPEARE
分类号 C07D217/04;A61K31/00;A61K31/44;A61K31/4427;A61K31/4433;A61K31/4436;A61K31/445;A61K31/47;A61K31/472;A61K31/4725;A61K31/4738;A61K31/4745;A61K31/495;A61K31/535;A61K31/5375;A61K31/5383;A61K31/55;A61K31/551;A61K31/5513;A61K31/553;A61P9/00;A61P25/04;C07D217/02;C07D223/16;C07D243/14;C07D267/14;C07D281/10;C07D409/12;C07D413/12;C07D413/14;C07D417/12;C07D455/04;C07D471/04;C07D487/04;C07D489/04;C07D498/04;C07D513/04;(IPC1-7):C07D409/12 主分类号 C07D217/04
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