发明名称 |
Encapsulated and non-encapsulated nitric oxide generators used as antimicrobial agents |
摘要 |
This invention relates to compositions capable of releasing nitric oxide and therapeutic methods of use thereof for the treatment of microorganism-related disease states. The composition comprises one or more nitric oxide generators, preferably encapsulated in vesicles, such as liposomes. The compositions are used therapeutically by administration to humans and animals via different routes for the treatment of infectious diseases caused by pathogenic microbes.
|
申请公布号 |
US5814666(A) |
申请公布日期 |
1998.09.29 |
申请号 |
US19950428632 |
申请日期 |
1995.04.24 |
申请人 |
THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES;ENTREMED, INC. |
发明人 |
GREEN, SHAWN J.;KEEFER, LARRY K. |
分类号 |
A61K9/127;A61K31/13;A61K31/14;A61K31/495;(IPC1-7):A61K31/13 |
主分类号 |
A61K9/127 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|