发明名称 |
Production of interferon- beta (IFN- beta ) in E. coli |
摘要 |
Methods for the production of interferon- beta polypeptides by bacterial cells, by culturing cells capable of producing IFN- beta polypeptide under conditions that induce increased production of IFN- beta polypeptide. Such conditions include, for example, low potassium cation concentration and/or very low sodium cation concentration and/or specific pH ranges.
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申请公布号 |
US5814485(A) |
申请公布日期 |
1998.09.29 |
申请号 |
US19950477310 |
申请日期 |
1995.06.06 |
申请人 |
CHIRON CORPORATION |
发明人 |
DORIN, GLENN;MCALARY, PATRICK J.;WONG, KATHLEEN M. |
分类号 |
C12N15/09;A61K38/21;C07K14/565;C12N1/21;C12N15/22;C12P21/02;C12R1/19;(IPC1-7):C12N15/22 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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