NOVEL 1,4-BENZOTHIAZEPIN 1,1-DIOXIDES, METHOD OF OBTAINING THEM, PHARMACEUTIC AGENT, THERAPEUTIC PROCESS EMPLOYING THEM AND THEIR APPLICATION IN PRODUCTION OF A PHARMACEUTIC AGENT

摘要

The present invention is concerned with new hypolipidemic compounds (I) and with their use in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions, such as atherosclerosis. Compounds of the formula (I): wherein X is -NH- or -O-; and R<7> is a group of the formula wherein the hydroxyl groups may be substituted by acetyl or benzyl, or -(C1-C6)-alkyl-R<17> wherein the alkyl group may be substituted with one or more hydroxyl groups; R<16> is -COOH or -CH2-OH; R<17> is H, -OH, -NH2, -COOH or COOR<18>; R<18> is (C1-C4)-alkyl or -NH-(C1-C4)-alkyl.