ULTRASONIC ALTERNATIVE TO LASER-BASED PHOTODYNAMIC THERAPY

摘要

Disclosed is a method for activating photosensitive therapeutic, and other compounds comprising the steps of providing a photosensitive therapeutic compound in combination with an appropriate solvent such as dimethyl phthalate (DAMP); generating acoustic energy for generating free radicals from the solvent and reacting the free radicals with an oxalate ester to generate a key intermediate; transferring chemical energy to the photosensitive therapeutic compound from the key intermediate; and activating the photosensitive compound with the transferred energy.