DISPOSABLE MICROTIP PROBE FOR LOW FLOW ELECTROSPRAY

摘要

An Electrospray probe (1) which includes a replaceable or disposable micron size diameter Electrospray tip (2) used for low flow rate Electrospray has been developed. The replaceable microtip (2) can be safely removed from the Electrospray (ES) chamber (4) without turning off high voltage within the chamber (4). Telescoping support ways (20) have been included to prevent ES tip (2) damage by guiding the ES probe tip (2) during removal from and insertion into the ES chamber (4). The replaceable microtip (2) is held in a fixed position during operation with a collet assembly which also provides electrical contact with coated microtips. The replaceable microtip ES probe assembly (1) is compatible with microtips (2) that are metal or coated or uncoated glass materials. For uncoated glass microtips (2) the ES probe assembly (1) accommodates a wire electrical contact which is installed in the replaceable microtip bore.