发明名称 |
Improved process for the preparation of trifluoromethyloxirane |
摘要 |
Preparation of trifluoromethyl-oxirane (I) comprises: (i) reducing 3-chloro-1,1,1-trifluoroacetone (II) in the presence of an inert solvent; (ii) treating the reaction mixture with a proton source to give 3-chloro-1,1,1-trifluoro-2-propanol; and (iii) cyclising (III) with elimination of hydrogen chloride, using aqueous alkali. |
申请公布号 |
EP0866064(A1) |
申请公布日期 |
1998.09.23 |
申请号 |
EP19980104140 |
申请日期 |
1998.03.09 |
申请人 |
BAYER AG |
发明人 |
ROCK, MICHAEL-HAROLD, DR.;LUI, NORBERT, DR. |
分类号 |
C07D301/26;C07D301/28;C07D303/08 |
主分类号 |
C07D301/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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