摘要 |
Selective labelling of proteins (I) that contain selenocysteine (SeCys) and/or Cys residues, optionally in oxidised form, comprises; (i) at least one incubation of a (I)-containing sample with at least one modifying agent (II) specific for SeCys or Cys, and (ii) at least one incubation with at least one labelling reagent (III) with similar specificity, provided that before, during and/or after at least one incubation, a substance (IV), that interacts with (I), is added.
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申请人 |
IHF INSTITUT FUER HORMON- UND FORTPFLANZUNGSFORSCHUNG, 22529 HAMBURG, DE;EVOTEC BIOSYSTEMS GMBH, 22529 HAMBURG, DE |
发明人 |
WILLEY, KEVAN, DR., 22393 HAMBURG, DE;OBERMANN-PLES, HEIKE, DR., 21335 LUENEBURG, DE;HUNT, NICHOLAS, DR., 21629 NEU WULMSTORF, DE;HENCO, KARSTEN, DR., 40699 ERKRATH, DE |