发明名称 |
Protecting group for synthesizing oligonucleotide analogs |
摘要 |
A 2-N-amidoethyl protected nucleoside analog phosphoramidite of formula (1): is useful in the synthesis of a wide variety of oligonucleotide analogs. Coupling yields with phosphoramidite (1) in solution or solid phase oligonucleotide analog synthesis are high and the 2-N-amidoethyl protecting group can be removed easily under standard conditions. |
申请公布号 |
AU6679898(A) |
申请公布日期 |
1998.09.22 |
申请号 |
AU19980066798 |
申请日期 |
1998.03.03 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
ZACHARIA S. CHERUVALLATH;DANIEL C. CAPALDI;VASULINGA T. RAVIKUMAR;DOUGLAS L. COLE |
分类号 |
C07C253/00;C07C255/50;C07H19/10;C07H19/20;C07H21/00 |
主分类号 |
C07C253/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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