发明名称 |
Compounds for the prevention and treatment of helmith infections |
摘要 |
A compound for protecting a vertebrate against infection by helminths comprising hyaluronidase covalently coupled to an immunostimulating carrier, in preferred form, the immunostimulating carrier to which the hyaluronidase is covalently coupled comprising a copolymer of ethylenepiperazine N-oxide and N-ethylacetylethylenepiperazinium bromide (hereafter referred to as "SYNPOL"), and a process for protecting a vertebrate against infection by helminths comprising administration to the vertebrate of a therapeutically effective amount of a compound comprising hyaluronidase covalently coupled to an immunostimulating carrier, preferably SYNPOL, in preferred form, the compound being administered to the vertebrate in the form of a vaccine.
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申请公布号 |
US5811100(A) |
申请公布日期 |
1998.09.22 |
申请号 |
US19960655282 |
申请日期 |
1996.05.15 |
申请人 |
PETROVAX, INC. |
发明人 |
DAUGALIEVA, EMMA K.;NEKRASOV, ARKADY V.;PETROV, REM V.;KHAITOV, RAKHIM M.;ATAULLAKHANOV, RAVSHAN I. |
分类号 |
A61K45/00;A61K35/12;A61K35/56;A61K39/00;A61K39/385;A61K39/39;A61K47/34;A61P33/02;C08F226/06;C08G73/06;C12N11/08;(IPC1-7):A61K39/385;A61K38/00;C07D243/08 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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