| 发明名称 |
Proteins with mutations to decrease N-terminal methylation |
| 摘要 |
Mutated protein having a sequence with a non-proline amino acid replacement for a proline at amino acid position 4. The mutated protein is not methylated on its N-terminus when expressed in bacteria. The mutated protein is a mutation of a methylated protein that is at least partially methylated on its N-terminus when expressed in bacteria.
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| 申请公布号 |
US5811264(A) |
申请公布日期 |
1998.09.22 |
| 申请号 |
US19960609271 |
申请日期 |
1996.02.29 |
| 申请人 |
SOMATOGEN, INC. |
发明人 |
AITKEN, JACQUELINE F.;APOSTOL, IZYDOR Z.;LIPPINCOTT, JULIE A.;LEVINE, JOSEPH D. |
| 分类号 |
A61K38/00;C07K14/805;C12N15/10;(IPC1-7):C12P21/06;C07K14/00;C07K14/05 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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