发明名称
摘要 PURPOSE:To safely maintain the antibacterium performance for a long period and obviate the need of taking account of the contamination by the sundry germs as in the conventional living body material and facilitate handling by loading the antibacterium metal ions and setting the loading quantity of the antibacterial metal ions to 5-0.0001wt.% for the hydroxyapatite. CONSTITUTION:A living body material in which the sundry germs having the living body affinity easily breed such as hydroxy-apatite is deformed, and the denatured hydroxyapatite which is added with the antibacterium performance is prepared, keeping the living body affinity, and used as living boyd material. The antibacterial hydroxyapatite is stabilized by substituting a part of the Ca ions of the hydroxyapatite represented by Ca10(PO4)6(OH)2 or the apatites in which a part of OH of the hydroxyapatite is substituted by fluorine or iodine, by the antibacterial metal ions, and the antibacterial metal ions are introduced into the thin holes in the particle structure of the apatites. The antibacterial hydroxyapatite can be easily prepared by allowing the antibacterial metal salts to coexist in the synthesis of the hydroxyapatite or reacting the metal salt with the hydroxyapatite.
申请公布号 JP2801022(B2) 申请公布日期 1998.09.21
申请号 JP19890122958 申请日期 1989.05.18
申请人 发明人
分类号 A61K6/00;A01N59/16;A61K6/033;A61L27/00;C01B25/32 主分类号 A61K6/00
代理机构 代理人
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