发明名称 USE OF 2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES FOR THE MANUFACTURE OF A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF SLEEP DISORDERS
摘要 The present invention provides novel uses of the compounds of general formula (I) wherein R3 is hydrogen, alkyl or cycloalkyl; R4 is hydrogen or R4 together with R10 represents a bridge; R7 is hydroxy or alkoxy; R10, R11, R12 independently represent hydrogen, trifluoromethyl, halogen or alkyl; or R10 together with R11 represents a bridge, or R11 together with R12 represents a bridge, the bridge in both cases being chosen among -O-CH2-CH2-, -O-CH2-CH2-CH2-, -O-CH=CH-, -CH2-CH2-CH2-, -CH2-CH=CH- or -CH2-CH2-CH2-CH2-; R13 is hydrogen, halogen or alkyl; and pharmaceutically acceptable salts thereof in combination with a pharmaceutically acceptable carrier for the manufacture of a pharmaceutical composition for treatment of sleep disorders and/or sleep disturbances.
申请公布号 CA2283083(A1) 申请公布日期 1998.09.17
申请号 CA19982283083 申请日期 1998.03.11
申请人 NOVO NORDISK A/S 发明人 FINK-JENSEN, ANDERS;FOGED, CHRISTIAN
分类号 C07D223/16;A61K31/55;A61P25/20;C07D405/04;(IPC1-7):A61K31/55 主分类号 C07D223/16
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